教育背景

起止时间 毕业院校 专业

博士 2000.09-2003.08 中国科学院动物研究所 生理学

硕士 1994.09-1997.07 wnsr888威尼斯 发育生物学

本科 1990.09-1994.07 wnsr888威尼斯 生物化学

工作经历

2011.02- wnsr888威尼斯 副教授

2003.09-2010.10 日本名古屋大学医学部 COE研究员（博士后）及研究员

1997.08-2000.08 山东省医学科学院生物技术研究中心 助理研究员

科研方向

1.体重调节与肥胖发生的分子机制研究

2.基因敲除小鼠模型的制备及其研究

主持课题

1.2014.01—2017.12 Rcan2基因的两种剪切变体在肥胖发生中的作用研究 国家基金面上项目

2.2013.10—2016.10 Rcan2基因的不同剪切变体在体重调节机制中的作用 省基金面上项目

3.2012.01—2012.12 下丘脑中Rcan2调控摄食和促进体重增长的分子机制研究 国家基金主任基金项目

研究成果

1.J. H. Duncan Bassett, John G. Logan, Alan Boyde, Moira S. Cheung, Holly Evans, Peter Croucher,Xiao-yang Sun, Sai Xu, Yoshiharu Murata, and Graham R. Williams. Mice lacking the calcineurin inhibitor Rcan2 have an isolated defect of osteoblast function.Endocrinology. 2012 153(7):3537-48

2.Xiao-yang Sun, Yoshitaka Hayashi, Sai Xu, Yasuhiko Kanou, Yoshiko Takagishi, Ya-ping Tang and Yoshiharu Murata. Inactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake.PLoS One. 2011,6(1):e14605.

3.Xiao-yang Sun, Yoshiko Takagishi, Erina Okabe, Yuko Chishima, Yasuhiko Kanou, Shiori Murase, Kazue Mizumura, Mie Inaba, Yukio Komatsu, Yoshitaka Hayashi, Elior Peles, Sen-ichi Oda, and Yoshiharu Murata. A Novel Caspr Mutation Causes the Shambling Mouse Phenotype by Disrupting Axoglial Interactions of Myelinated Nerves.Journal of Neuropathology and Experimental Neurology. 2009, 68 (11) : 1207-1218

4.Xiao-yang Sun, Zi-yan Chen, Yoshitaka Hayashi, Yasuhiko Kanou,Y. Takagishi, Sen-ichi Oda, and Yoshiharu Murata. Insertion of an intracisternal A particle retrotransposon element in plasma membrane calcium ATPase 2 gene attenuates its expression and produces an ataxic phenotype in joggle mutant mice.Gene.2008, 411: 94-102.

5.Xiao-yang Sun, Zi-yan Chen,Yasuhiko Kanou,Y. Takagishi,Yoshitaka Hayashi, T. Ohno,Yoshiharu MurataandSen-ichi Oda. Mapping of jog locus to the region between D6Mit104 and D6Mit336 on mouse chromosome 6.Experimental Animals. 2007，56 ：389-392.

6.Xiao-yang Sun, Fei-xue Li , Jun Li, Yin-fei Tan, Yun-shang Piao, Shuang Tang, Yan-ling Wang. Determination of Genes Involved in the Early Process of Embryonic Implantation in Rhesus Monkey (Macaca mulatta) by Suppression-Subtractive Hybridization.Biology of Reproduction. 2004, 70(5):1365-1373