王德华
wnsr888威尼斯 特聘教授
通讯地址:山东省青岛市即墨区滨海路72号 (邮编 266237)
E-mail: dehuawang@sdu.edu.cn
教育背景:
1990/08—1993/06,博士,北京师范大学生物系, 动物生理生态学
1985/07—1988/10,硕士,中国科学院西北高原生物研究所, 动物生理生态学
1981/08—1985/06,学士,山东师范大学生物系, 生物学
工作经历:
2021/06 — 至今,wnsr888威尼斯特聘教授
2000/10 — 2021/06,中国科学院动物研究所研究员、二级研究员、中国科学院特聘研究员、中国科学院大学岗位教授等
1995/10—2000/10,中国科学院动物研究所副研究员
1993/07—1995/07,中国科学院动物研究所博士后
1988/10—1990/08,中国科学院西北高原生物研究所助理研究员
科研方向:
以野生恒温动物为研究对象,实验室研究与野外研究相结合,利用生理学、分子生物学、神经生物学和组学等方法和技术手段,从分子、组织、器官、个体以及种群等不同组织层次上,研究动物对环境的生理适应策略。
主要研究兴趣:
1. 野生动物的能量代谢与体温调节
2. 野生动物的行为学与生理学基础
3. 野生动物的肠道菌群与生理功能
(招收以上各研究方向的硕士、博士研究生和博士后研究人员)
主持课题:
1. 2024.1- 2028.12 国家自然科学基金重点项目:小型哺乳动物繁殖与产热对光周期的反应模式及机制。主持。
2. 2023.1- 2026.12 国家自然科学基金面上项目:内蒙古草原两种啮齿动物肠道菌群对消化生理的影响。 主持。
3. 2021.6-2022.5中国科学院B类先导科技专项培育项目:生物互作机制的解构与设计— 农业有害生物的智慧型防控。子课题主持。
4. 2020.1- 2023.12 国家自然科学基金面上项目:小型哺乳动物的温感TRPs 通道及其在体温调节中的作用。主持。
5. 2020.1-2022.12科技部科技基础资源调查专项:农牧交错带有害动物物种多样性调查。课题主持。
6. 2018.01 - 2021.12 国家自然科学基金面上项目:布氏田鼠聚群的能量学、社会缓冲效应及其神经基础。主持。
7. 2015.1-2018.12国家自然科学基金面上项目:长爪沙鼠能量和水代谢特征的地理差异。主持。
8. 2013.1-2016.12国家自然科学基金面上项目:长爪沙鼠热中性区内代谢和体温调节的分子生理学。主持。
9. 2011.1 -2013.12 国家自然科学基金面上项目:内蒙古草原两种啮齿动物储食行为的生理学机理。主持。
10. 2011.1-2014.12中国科学院知识创新工程重要方向项目:重大虫鼠害暴发规律与成灾机制。课题主持。
11. 2007.1- 2010.12 国家杰出青年科学基金:个体和生理生态学。主持。
12. 2007.1-2012.12科技部973 项目:农业鼠害暴发成灾规律、预测及可持续控制的基础研究-鼠类种群暴发的生理与免疫调节机制。课题主持。
13. 2005.1 - 2008.12 国家自然科学基金委重点项目:内蒙古草原两种啮齿动物的产热和能量代谢的机理研究。主持。
14. 2001.11—2004.11中国科学院知识创新工程重要方向项目:种群暴发和崩溃的机理研究。项目首席科学家。
15. 2002.1—2004.12 国家自然科学基金:内蒙古两种啮齿动物的能量平衡和体重调节。主持。
16. 2000.1-2002.12 国家自然科学基金: 食物质量对两种啮齿动物的消化对策和能量代谢的影响。主持。
17. 1998.1-2000.12 国家自然科学基金: 内蒙古草原两种啮齿动物的能量代谢和生态进化意义。主持。
荣誉和奖励:
2021年:中国科学院优秀导师
2014年:中国科协“全国优秀科技工作者”
2008年:享受国务院政府特殊津贴
2007年:“新世纪百千万人才工程”国家级人选
2006年:国家杰出青年科学基金获得者
2006年:中国科学院研究生院优秀教师
社会兼职:
中国动物学会理事、常务理事
国际生理学联合会(IUPS)比较生理学委员会委员(2023— )
中国动物学会兽类学分会主任委员 (2023— )
中国动物学会动物生理生态学分会主任委员(2023—)
中国生理学会比较生理学委员会主任委员 (2023— )
中国动物学会副理事长(2009 — 2019)
中国动物学会秘书长 (2014 — 2019)
中国生态学会动物生态专业委员会主任 (2005 — 2017)
《兽类学报》主编 (2005 — )
Journal of Animal Ecology, Associate editor (2013— 2023)
Frontiers in Physiology (Integrative physiology), Associate editor(2019— )
Hormones and Behavior 编委(2007— )
Physiology and Behavior 编委 (2023— )
Journal of Comparative Physiology B 编委 (2023— )
Integrative Zoology 编委 (2012— )
Journal of Thermal Biology 编委 (2013— )
Journal of Experimental Biology 编委 (2017— )
Journal of Experimental Zoology A 编委 (2017— )
Comparative Biochemistry and Physiology (A、B、C和D卷) 编委 (2018— )
Frontiers in Neuroscience (Gut-Brain Axis), Review editor (2021— )
PloS One, Academic editor
《生态学报》编委
《动物学杂志》编委
《中国科技术语》编委
代表性学术论文:
(在国内外学术期刊上发表学术论文200余篇)
1. Bo TB*, Tang LQ, Xu XM, Liu M, Wen J, Lv JZ and Wang DH* 2023. Role of gut microbiota in the postnatal thermoregulation of Brandt’s voles. Cell Reports, 42:113021. https://doi.org/10.1016/j.celrep.2023.113021
2. Zhang XY*, Khakisahneh S, Liu W, Zhang XY, Zhai WW, Chen JL, JR Speakman* and Wang DH*. 2023. Phylogenetic signal in gut microbial community rather han in rodent metabolic traits. National Science Review 10: nwad209. https://doi.org/10.1093/nsr/nwad209
3. Speakman JR*, Chi QS, Ołdakowski L, Fu HB, Fletcher QE, Hambly C, Togo J, Liu XY, Piertney SB, Wang XH, Zhang LZ, Redman P, Wang L, Tang GB, Li YG, Cui JG, Thomson PJ, Wang ZL, Glover P, Robertson OC, Zhang YM*, and Wang DH* 2021 Surviving winter on the Qinghai-Tibetan Plateau: pikas suppress energy demands and exploit yak feces to survive winter. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2100707118
4. Khakisahneh S, Zhang XY, Nouri Z and Wang DH* 2021 Cecal microbial transplantation attenuates hyperthyroid-induced thermogenesis in Mongolian gerbils. Microbial Biotechnology. doi:10.1111/1751-7915.13793
5. Bo TB, Zhang XY, Kevin K, Wen J, Tian SJ and Wang DH*. 2020 Coprophagy prevention alters microbiome, metabolism, neurochemistry, and cognitive behavior in a small mammal. The ISME Journal, 14:2625-2645. (doi.org/10.1038/s41396-020-0711-6)
6. Khakisahneh S, Zhang XY, Zouri Z and Wamg DH* 2020 Gut microbiota and host thermoregulation in response to ambient temperature fluctuations. mSystem 5: e00514-20.
7. Bo TB, Zhang XY, Wen J, Deng K, Qin XW and Wang DH*. 2019. The microbiota–gut–brain interaction in regulating host metabolic adaptation to cold in male Brandt’s voles (Lasiopodomys brandtii). The ISME Journal 13:3037-3053 (doi.org/10.1038/s41396-019-0492-y)
8. Sukhchuluun G, Zhang XY, Chi QS and Wang DH* 2018 Huddling conserves energy, decrease core body temperature, but increases activity in Brandt’s voles (Lasiopodomys brandtii). Frontiers in Physiology 9:563 (doi:10.3389/fphys.2018.00563).
9. Zhang XY, G. Sukhchuluun, Bo TB, Chi QS, Yang JJ, Chen B, Zhang L and Wang DH* 2018. Huddling remodels gut microbiota to reduce energy requirements in a small mammal species during cold exposure. Microbiome 6:126. (doi: 10.1186/s40168-018-0509-1)
10. Zhang XY, Lou MF, Shen W, Fu RS and Wang DH*. 2017. A maternal low-fiber diet predisposes offspring to improved metabolic phenotypes in adulthood in an herbivorous rodent. Physiological and Biochemical Zoology, 90(1) : 75-84.
11. Chi QS, Wan XR, Geiser F and Wang DH*. 2016. Fasting-induced daily torpor in desert hamsters (Phodopus roborovskii). Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology 199:71-77.
12. Xu MM, Wang DH*. 2016. Water deprivation up-regulates urine osmolality and renal aquaporin 2 in Mongolian gerbils (Meriones unguiculatus). Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology 194:37-44.
13. Shi YL, Chi QS, Liu W, Fu HP and Wang DH*. 2015. Environmental metabolomics reveal geographic variation in aerobic metabolism and metabolic substrates in Mongolian gerbils (Meriones unguiculatus). Comp Biochem Physiol D 14: 42-52.
14. Shen W, Zhang XY, Liu DZ and Wang DH*. 2015. Hormones orchestrated pre- and post-copulatory sexual traits in male Mongolian gerbils. Physiol Behav. 143:90-96.
15. Zhang Q, Lin Y, Zhang XY and Wang DH*. 2015. Cold exposure inhibits hypothalamic Kiss-1 gene expression, serum leptin concentration, and delays reproductive development in male Brandt’s vole (Lasiopodomys brandtii). Int J Biometeorol. 59(6): 679-691.
16. Xu YC., Yang DB, Speakman JR. and Wang DH*. 2014. Oxidative stress in response to natural and experimentally elevated reproductive effort is tissue dependent. Functional Ecology, 28:402-410.
17. Yang HD, Wang Q and Wang DH*. 2014. Food hoarding, but not food intake, is attenuated by acute diazepam treatment in female Mongolian gerbils (Meriones unguiculatus). Hormones and Behavior, 66: 186-195.
18. Pan Q, M Li, YL Shi, HW Liu, JR Speakman and Wang DH*. 2014. Lipidomics reveals mitochondrial membrane remodeling associated with acute thermoregulation in a rodent with a wide thermoneutral zone. Lipid, 49:715-730.
19. Yang DB., Xu YC., Wang DH.* and JR Speakman. 2013. Effects of reproduction on immuno-suppression and oxidative damage, and hence support or otherwise for their roles as mechanisms underpinning life history tradeoffs, are tissue and assay dependent. Journal of Experimental Biology, 216:4242-4250.
20. Liu QS, ZQ Zhang, Caviedes-Vidal E and Wang DH* 2013 Seasonal plasticity of gut morphology and small intestinal enzymes in free-living Mongolian gerbils. J Comp Physiol B 183:511–523
21. Yang DB, Xu YC and Wang DH*. 2012. Partial removal of brown adipose tissue enhances humoral immunity in warm-acclimated Mongolian gerbils (Meriones unguiculatus), General and Comparative Endocrinology, 175:144-152.
22. Zhang XY, Zhang Q and Wang DH*. 2011. Pre- and post-weaning cold exposure does not lead to an obese phenotype in adult Brandt's voles (Lasiopodomys brandtii). Hormones and Behavior. 60:210–218.
23. Yang HD, Wang Q, Wang ZX and Wang DH*. 2011. Food hoarding and associated neuronal activation in brain reward circuitry in Mongolian gerbils. Physiol Behav. 104(3):429-436.
24. Liu XY, Wang DH*. 2011. Effects of leptin supplementation to lactating Brandt's voles (Lasiopodomys brandtii) on the developmental responses of their offspring to a high-fat diet. J Comp Physiol B. 181(6):829-839.
25. Cui JG, Tang GB, Wang DH * and JR Speakman. 2011. Effects of leptin infusion during peak lactation on food intake, body composition, litter growth and maternal neuroendocrine status in female Brandt’s voles (Lasiopodomys brandtii). American Journal of Physiology: Regul Integr Comp Physiol 300:R447-459.
26. Chi QS and Wang DH*. 2011. Thermal physiology and energetics in male desert hamsters (Phodopus roborovskii) during cold acclimation. J Comp Physiol B. 181: 91-103.
27. Xu DL, Liu XY and Wang DH *. 2011. Food restriction and refeeding has no effect on cellular and humoral immunity in Mongolian gerbils (Meriones unguiculatus). Physiological and Biochemical Zoology. 84(1): 87-98.
28. Li YG, Yan ZC and Wang DH*.2010. Physiological and biochemical basis of basal metabolic rates in Brandt's voles (Lasiopodomys brandtii) and Mongolian gerbils (Meriones unguiculatus) Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology 157:204-211.
29. Tang GB Cui JG and Wang DH*.2009. The role for hypoleptinemia in cold adaptation in Brandt's voles. American Journal of Physiology: Regul Integr Comp Physiol 297: R1293–R13.
30. Wu SH, Speakman JR and Wang DH*. 2009. Limits to sustained energy intake. XI. A test of the heat dissipation limitation hypothesis in lactating Brandt’s voles (Lasiopodomys brandtii). Journal of Experimental Biology 212:3455-3465.
31. Zhao ZJ, Chen JF and Wang DH*. 2009. Plasticity in the physiological energetics of Mongolian gerbils is associated with diet quality. Physiological and Biochemical Zoology, 82:504-515.
32. Zhang XY, Wang DH*. 2008. Different physiological roles of serum leptin in the regulation of energy intake and thermogenesis between pregnancy and lactation in primiparous Brandt's voles (Lasiopodomys brandtii). Comparative Biochemistry and Physiology. 148 : 390–400.
33. Lu Q, Zhong WQ and Wang DH*.2007. Effects of photoperiod history on body mass and energy metabolism in Brandt's voles (Lasiopodomys brandtii). Journal of Experimental Biology 210: 3838-3847.
34. Zhang XY, Wang DH*. 2007. Thermogenesis, food intake and serum leptin in cold-exposed lactating Brandt's voles (Lasiopodomys brandtii). The Journal of Experimental Biology. 210: 512-521.
35. Li FH, Zhong WQ, Wang ZX and Wang DH*. 2007. Rank in a food competition test and humoral immune functions in male Brandt's voles (Lasiopodomys brandtii). Physiology and Behavior. 90: 490-495.
36. Li XS, Wang DH*. 2007. Photoperiod and temperature can regulate body mass, serum leptin concentration, and uncoupling protein 1 in Brandt's voles (Lasiopodomys brandtii) and Mongolian gerbils (Meriones unguiculatus). Physiological and Biochemical Zoology. 80: 326-334.
37. Liu QS, Li JY and Wang DH*. 2007. Ultradian rhythms and the nutritional importance of caecotrophy in captive Brandt's voles (Lasiopodomys brandtii). Journal of Comparative Physiology B. 177(4):423-32.
38. Wang JM, Zhang YM, Wang DH*. 2006. Seasonal thermogenesis and body mass regulation in plateau pikas (Ochotona curzoniae). Oecologia. 149(3):373-82.
39. Zhang XY, Wang DH*. 2006. Energy metabolism, thermogenesis and body mass regulation in Brandt's voles (Lasiopodomys brandtii) during cold acclimation and rewarming. Hormone and Behavior. 50(1):61-9.
40. Zhao ZJ, Wang DH*. 2006. Short photoperiod influences energy intake and serum leptin level in Brandt's voles (Microtus brandtii). Hormone and Behavior. 49(4):463-9.
41. Zhao ZJ and Wang DH* 2005 Short photoperiod enhances thermogenic capacity in male and female Brandt's voles. Physiology and Behavior 85:143-149.
42. Li XS and Wang DH* 2005 Regulation of body weight and thermogenesis in seasonally acclimatized Brandt’s voles (Microtus brandti). Hormones and Behavior 48:321-328.
43. Song ZG and Wang DH* 2002. The maximum metabolizable energy intake and the relationship with basal metabolic rate in the striped hamster (Cricetulus barabensis). Acta Theriologica, 47(4):417-423.
44. Pei YX, Wang DH* and I.Hume. 2001. Selective digesta retention and coprophagy in Brandt’s vole (Microtus brandti). Journal of Comparative Physiology B. 171: 457-46.
45. Pei YX, Wang DH* and I. Hume. 2001. Effects of dietary fibre on digeta passage, nutrient digestibility, and gastrointestinal tract morphology in the granivorous Mongolian gerbil (Meriones unguiculatus). Physiological Biochemical Zoology 74(5):742-749.
46. Wang DH, Sun RY, Wang ZW and Liu JS. 1999. Effects of photoperiod and temperature on thermogenic characteristics in plateau pikas and root voles. Journal of Comparative Physiology B 169:77-83.
47. Wang DH and Wang ZW 1996. Seasonal variations in thermogenesis and energy reguirements of plateau pikas (Ochotona curzoniae) and root voles (Microtus oeconomus). Acta Theriologica 41:225-236.
48. 王德华、孙儒泳、王祖望 1996 根田鼠哺乳期的同化能及产后生长发育过程中的能量分配。动物学报,42:140-145。
49. 王德华、王祖望 1990 小哺乳动物在高寒环境中的生存对策Ⅱ.高原鼠兔和根田鼠非颤抖性产热 (NST) 的季节性变化。兽类学报 10:40-53。
50. 王德华、王祖望 1989 小哺乳动物在高寒环境中的生存对策I.高原鼠兔和根田鼠褐色脂肪组织 (BAT) 重量和显微结构的季节性变化。兽类学报 9:176-185。
著作和译著:
1. 孙儒泳、王德华、牛翠娟、刘定震、张立 (主编) 动物生态学原理(第四版)。 北京:北京师范大学出版社,2019。
2. 王德华(译) 如何做生态学。北京:高等教育出版社,2010。
3. 李博、张大勇、王德华 (主译) 生态学:从个体到生态系统。北京:高教出版社,2016。
4. 王德华 (译) 如何做生态学(第二版)。 北京:高等教育出版社,2022。
5. 王德华、王祖望 (主编) 中国动物学学科史。北京:中国科学技术出版社,2022。