王官锋 教授
E-Mail：gfwang@sdu.edu.cn
个人简介
王官锋，wnsr888威尼斯“齐鲁青年学者”特聘教授，博士生导师。担任中国生物工程学会农业分会委员，中国植物病理学位青年委员会委员，中国植物保护学会青年委员会委员，山东省植物生理学会常务理事；山东省植物病理学会理事；国际植物病理杂志Molecular Plant-Microbe Interactions编委；多个国际期刊的审稿人。
教育背景
2005 – 2009，中国科学院遗传与发育生物学研究所，遗传学，博士
2002 – 2005，南京农业大学，作物遗传育种，硕士
1998 – 2002，山东农业大学，农学师范，学士
工作经历
2015 - 至今，wnsr888威尼斯，教授
2011 – 2015，美国北卡罗来纳州立大学，博士后
2009 – 2011，美国马里兰大学巴尔的摩郡，博士后
科研方向
1. 以玉米为主要研究材料，综合运用遗传学、生物化学、分子生物学和生物信息学等方法，针对玉米主要病害（如大小斑病、茎腐病等）开展抗病信号通路中重要基因的发掘和分子机理解析。
2. 利用玉米中一个能引起自主性超敏感防卫反应的突变体作为工具，研究植物超敏感防卫反应的分子机理。
3. 玉米 NLR 类免疫受体 Rp1-D21 的调控机理研究。
4. 轮枝镰孢菌的致病机理研究。
主持课题
1. 2022-2027，玉米抗大、小斑病等关键基因的挖掘与鉴定，“十四五”国家重点研发计划，子课题主持；
2. 2021-2024，泛素连接酶支架蛋白在玉米免疫受体Rp1-D21所介导抗病防卫反应中的功能与分子机理研究，国家自然科学基金面上项目，主持；
3. 2019-2022，内体分选转运复合体I关键组分在玉米抗病防卫反应中的功能解析，国家自然科学基金面上项目，主持；
4. 2016- 2020，“小麦等作物功能基因组研究与应用”子课题三，玉米产量、品质性状的功能基因组与调控网络，“十三五”国家重点研发计划，项目骨干；
5. 2016-2019，玉米NB-LRR类抗病基因Rp1-D21介导的超敏感反应的分子机理，国家自然科学基金面上项目，主持；
6. 2015-2020，玉米抗病分子机理研究，“齐鲁青年学者”建设经费，主持。
本课题组常年招聘博士后，待遇优渥，欢迎邮件联系！
· (*: 通讯作者；#：共同第一作者)
1. Yang Sun, Shijun Ma, Xiangguo Liu, Guan-Feng Wang*. 2023. The maize ZmVPS23-like protein relocalizes the NLR protein Rp1-D21 to the endosomes and suppresses the defense response. The Plant Cell 35: 2369-2390.
2. Ya-Jie Li#, Jin-Ming Gu#, Shijun Ma#, Yang Xu, Mengjie Liu, Chuang Zhang, Xiangguo Liu, Guan-Feng Wang*. 2023. Genome editing of the susceptibility gene ZmNANMT confers multiple disease resistance without agronomic penalty in maize. Plant Biotechnology Journal 21:1525-1527.
3. Yang Sun, Yu-Xiu Zhu, Peter J. Balint-Kurti, Guan-Feng Wang*. 2020. Fine-tuning immunity: players and regulators for plant NLRs. Trends in Plant Science 25: 695-713.
4. Qing-Ling Luan#, Yu-Xiu Zhu#, Shijun Ma, Yang Sun, Xiao-Ying Liu, Mengjie Liu, Peter J. Balint-Kurti, Guan-Feng Wang*. 2021. Maize metacaspases modulate the defense response mediated by the NLR protein Rp1-D21 likely by affecting its subcellular localization. The Plant Journal 105:151-166.
5. Mengjie Liu, Ya-Jie Li, Yu-Xiu Zhu, Yang Sun, Guan-Feng Wang*. 2021. Maize nicotinate N-methyltransferase interacts with the NLR protein Rp1-D21 and modulates the hypersensitive response. Molecular Plant Pathology 22:564-579.
6. Chunxia Ge#, Yi-Ge Wang#, Shouping Lu, Xiangyu Zhao, Bing-kai Hou, Peter Balint-Kurti, Guan-Feng Wang*. 2021. Multi-omics analyses reveal the regulatory network and the function of ZmUGTs in maize defense response. Frontiers in Plant Science, 12: 738261.
7. Jinghua Zhang#, Xingmeng Jia#, Guan-Feng Wang, Shijun Ma, Shunxi Wang, Qin Yang, Xueyan Chen, Yuqian Zhang, Yajing Lyu, Xiaoxu Wang, Jiawei Shi, Yangtao Zhao, Yanhui Chen, Liuji Wu*. 2022. Ascorbate peroxidase 1 confers resistance to southern corn leaf blight in maize. Journal of Integrative Plant Biology 64:1196-1211.
8. Yu-Xiu Zhu, Chunxia Ge, Shijun Ma, Xiao-Ying Liu, Mengjie Liu, Yang Sun, Guan-Feng Wang*. 2020. Maize ZmFNSI homologs interact with an NLR protein to modulate hypersensitive response. International Journal of Molecular Sciences 21: 2529.
9. Chunxia Ge, Chaoxiao Tang, Yu-Xiu Zhu, Guan-Feng Wang*. 2021. Genome-wide identification of the maize 2OGD superfamily genes and their response to Fusarium verticillioides and Fusarium graminearum. Gene 764: 145078.
10. Shijun Ma, Hong Shi, Guan-Feng Wang*. 2021. The potential roles of different metacaspases in maize defense response. Plant Signaling & Behavior 16: e1906574.
11. Xu-Xu Huang , Yong Wang , Ji-Shan Lin , Lu Chen , Yan-Jie Li, Qian Liu , Guan-Feng Wang, Fang Xu, Lijing Liu, Bing-Kai Hou. 2021. The novel pathogen-responsive glycosyltransferase UGT73C7 mediates the redirection of phenylpropanoid metabolism and promotes SNC1-dependent Arabidopsis immunity. The Plant Journal. doi: 10.1111/tpj.15280.
12. Saet-Byul Kim, Lisa Van den Broeck, Shailesh Karre, Hoseong Choi, Shawn A Christensen, Guan-Feng Wang, Yeonhwa Jo, Won Kyong Cho, Peter Balint-Kurti. 2021. Analysis of the transcriptomic, metabolomic, and gene regulatory responses to Puccinia sorghi in maize. Molecular Plant Pathology 22:465-479.
13. Guan-Feng Wang*, Peter Balint-Kurti. 2016. Maize homologs of CCoAOMT and HCT, two key enzymes in lignin biosynthesis, form complexes with the NLR Rp1 protein to modulate the defense response. Plant Physiology 171: 2166-2177.
14. Guan-Feng Wang*, Jiabing Ji, Farid EI-Kasmi, Jeffery L. Dangl, Guri Johal, Peter Balint-Kurti*. 2015. Molecular and functional analyses of a maize autoactive NB-LRR protein identify precise structural requirements for activity. Plos Pathogens 11: e1004674.
15. Guan-Feng Wang*, Yijian He, Renee Strauch, Bode A Olukolu, Dahlia Nielsen, Xu Li, Peter Balint-Kurti*. 2015. Maize homologs of hydroxycinnamoyltransferase, a key enzyme in lignin biosynthesis, bind the nucleotide binding leucine-rich repeat Rp1 proteins to modulate the defense response. Plant Physiology 169: 2230-2243.
16. Bode A Olukolu#, Guan-Feng Wang#, Vijay Vontimitta#, Bala P Venkata, Sandeep Marla, Jiabing Ji, Emma Gachomo, Kevin Chu, Adisu Negeri, Jacqueline Benson, Rebecca Nelson, Peter Bradbury, Dahlia Nielsen, James B Holland, Peter J Balint-Kurti*, Gurmukh Johal. 2014. A genome-wide association study of the maize hypersensitive defense response identifies genes that cluster in related pathways. Plos Genetics 10: e1004562.
17. Guan-Feng Wang*, Peter Balint-Kurti*. 2015. Cytoplasmic and nuclear localizations are important for the hypersensitive response conferred by maize autoactive Rp1-D21 protein. Molecular Plant-Microbe Interactions 28: 1023-1031.
18. Guan-Feng Wang*, Renchun Fan, Xianping Wang, Daowen Wang*, Xiangqi Zhang*. 2015. TaSGT1 and TaRAR1 associate with TaHsp90 to function in bread wheat (Triticum aestivum L.) seedling growth and stripe rust resistance. Plant Molecular Biology 87: 577-589.
19. Adisu Negeri#, Guan-Feng Wang#, Larissa Benavente, Cromwell M. Kibiti, Vijay Chaikam, Guri Johal, Peter Balint-Kurti. 2013. Characterization of temperature and light effects on the defense response phenotypes associated with the maize Rp1-D21 gene. BMC Plant Biology 13:106.
20. Hua Lu*, Chong Zhang, Ute Albrecht, Rena Shimizu, Guanfeng Wang, Kim D. Bowman. 2013. Overexpression of a citrus NDR1 ortholog increases disease resistance in Arabidopsis. Frontiers in Plant Science, 4:157.
21. Guan-Feng Wang, Savanna Seabolt, Safae Hamdoun, Ng Gina, Jin Park, Hua Lu*. 2011. Multiple roles of WIN3 in regulating disease resistance, cell death, and flowering time in Arabidopsis. Plant Physiology 156:1508-1519.
22. Guan-Feng Wang#, Xuening Wei#, Renchun Fan, Huanbin Zhou, Xianping Wang, Chunmei Yu, Lingli Dong, Zhenning Dong, Xiaojie Wang, Zhensheng Kang, Hongqing Ling, Qian-Hua Shen, Daowen Wang*, Xiangqi Zhang*. 2011. Molecular analysis of common wheat genes encoding three types of cytosolic heat shock protein (Hsp90): functional involvement of cytosolic Hsp90s in the control of wheat seedling growth and disease resistance. New Phytologist 191: 418-431.
23. Chunmei Yu, Yiwen Li, Bin Li, Lifang Hao, Jing Chen, Weiqiang Qian, Shiming Li, Guanfeng Wang, Shiwei Bai, Hua Ye, Huanju Qin, Qianhua Shen, Liangbiao Chen, Aimin Zhang, Daowen Wang*. 2010. Molecular analysis of phosphomannomutase (PMM) genes reveals a unique PMM duplication event in diverse Triticeae species and the main PMM isozymes in bread wheat tissues. BMC Plant Biology 10: 214.
